The immune system consists of an elaborate orchestration of various cell types specialized for different molecular processes. Due to the spectrum of these specializations, immune cells represent an intriguing cell model to identify general molecular and cell biological principles. Given the availability of various recently established tools (such as the genetic modification and in vitro cultivation of hematopoietic precursor cells, and the engineering of defined tissue-mimetic in vitro microenvironments) I see the unique opportunity to use immune cells for the discovery of novel molecular principles. In particular, I am investigating during my postdoctoral research how immune cells position their nucleus to enable fast migration in three-dimensional environments.


Institute of Science and Technology Austria

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