September 22, 2016

First complete architecture of respiratory supercomplexes in mammalian mitochondria determined by IST Austria Professor Leonid Sazanov and his group

The respiratory chain consisting of several large protein assemblies, which are embedded in the mitochondrial lipid membrane, takes care of the energy production in human cells. These large electron transport chain complexes are organized in so-called supercomplexes (respirasomes). IST Austria Professor...

September 12, 2016

Johanna Mikl-Leitner visits IST Austria

Today Johanna Mikl-Leitner, Vice Governor of Lower Austria, paid a visit to the Institute of Science and Technology Austria (IST Austria) in Klosterneuburg. IST Austria President Thomas Henzinger, Vice President Michael Sixt, and Managing Director Georg Schneider welcomed her for a...

September  9, 2016

Synaptic connectivity motifs contribute to efficient memory storage and retrieval in hippocampus

The hippocampal CA3 region plays a key role in learning and memory. One of the most remarkable properties of the network is its ability to retrieve previously stored memories from incomplete or degraded versions, a phenomenon that is widely known as...

September  6, 2016

Structure of mammalian protein complex of respiratory chain finally solved at atomic level by IST Austria Professor Leonid Sazanov and collaborators

The mitochondrial Complex I plays a central role in cellular respiration and energy metabolism. The ~1 Megadalton L-shaped protein complex is the largest protein assembly of the respiratory chain and now the largest asymmetric membrane protein assembly solved to date. Professor...

August 24, 2016

New historical study on Nazi medical crimes in Gugging hospital released

In 2007 the Executive Committee of the Institute of Science and Technology Austria (IST Austria) commissioned the Viennese historian Herwig Czech to undertake a study on the Nazi medical crimes in the psychiatric hospital of Gugging. Prior to the founding of...

August 12, 2016

Global crosstalk limits gene regulation

Molecular recognition is fundamental to transcriptional regulation, the primary mechanism by which cells control gene expression. The specificity of this regulation originates in the binding interactions between special regulatory proteins, called transcription factors (TFs), and short regulatory sequences on the DNA,...

August 10, 2016

New algorithm for optimized stability of planar-rod objects | First-time mathematical formulation by IST Austria computer science professor Bernd Bickel solves problem of technical modelling

During the annual top conference of the Special Interest Group for Computer Graphics (SIGGRAPH) of the Association for Computing Machinery (ACM), which took place in Anaheim, USA, IST Austria Professor Bernd Bickel and his group present an algorithm that allows improved...

August  3, 2016

Federal Chancellor Christian Kern visits IST Austria

Yesterday in the morning Christian Kern, Chancellor of the Federal Republic of Austria, paid a visit to the Institute of Science and Technology Austria (IST Austria) in Klosterneuburg, Lower Austria. IST Austria President Thomas Henzinger and Managing Director Georg Schneider...

July  7, 2016

Temporal signaling pattern regulates a cell’s destiny

During the early development of multicellular animals, cell fate decisions have to be taken to determine what the final cells of the developing organism will be. The biological process responsible for the development of the organism is steered by signals...

June 28, 2016

IST Austria Evaluation: “An excellent start“

In today’s meeting the Council of Ministers of the Austrian Federal Government discussed the evaluation report of IST Austria. The institute is legally required to undergo an evaluation every four year. As is stipulated by law, the evaluation report will be passed on to the Austrian National Council. A top-class...

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