7. Oct 2019

Revisiting and Repurposing the Double Helix

Datum: 7. October 2019 | 16:00 – 17:00
Sprecher: Taekjip Ha, Johns Hopkins University
Veranstaltungsort: Raiffeisen Lecture Hall, Central Building

DNA is an iconic molecule that forms a double helical structure, providing the basis for genetic inheritance, and its physical properties have been studied for decades. In this talk, I will present evidence that sequence and methylation dependent physical properties of DNA such as flexibility and self-association may be important for biological functions. In addition, I will present a new application of DNA where mechanical modulations of cell behavior can be studied at the single molecule level using rupturable DNA tethers.