4. Dec 2020

Residual population dynamics as a window into neural computation

Datum: 4. December 2020 | 15:00 – 16:00
Sprecher: Valerio Mante, ETH Zurich
Veranstaltungsort: Online

Neural activity in frontal and motor cortices can be considered to be the manifestation of a dynamical system implemented by large neural populations in recurrently connected networks. The computations emerging from such population-level dynamics reflect the interaction between external inputs into a network and its internal, recurrent dynamics. Isolating these two contributions in experimentally recorded neural activity, however, is challenging, limiting the resulting insights into neural computations. I will present an approach to addressing this challenge based on response residuals, i.e. variability in the population trajectory across repetitions of the same task condition. A complete characterization of residual dynamics is well-suited to systematically compare computations across brain areas and tasks, and leads to quantitative predictions about the consequences of small, arbitrary causal perturbations.