Oct 7, 2019
Revisiting and Repurposing the Double Helix
Date: October 7, 2019 |
4:00 pm –
Speaker: Taekjip Ha, Johns Hopkins University
Location: Raiffeisen Lecture Hall, Central Building
DNA is an iconic molecule that forms a double helical structure, providing the basis for genetic inheritance, and its physical properties have been studied for decades. In this talk, I will present evidence that sequence and methylation dependent physical properties of DNA such as flexibility and self-association may be important for biological functions. In addition, I will present a new application of DNA where mechanical modulations of cell behavior can be studied at the single molecule level using rupturable DNA tethers.