How fast can a complex organism evolve by natural selection? How can the development of extraordinarily complex morphologies and behaviours be guided by a functional genome of ~108 bases - much less information than is held in a personal computer? Answering such questions requires a clear measure of the information held in an organism and in its genome. This issue is relevant not only to natural selection, but also to evolutionary computation, in which selection, mutation and recombination are used to evolve better algorithms.  Nick Barton and  Harold de Vladar are studying the relation between information, entropy, and fitness.