Tamar Friedlander

Postdoc

tamar.friedlander@remove-this.ist.ac.at

Research

Modeling biological systems is an intricate task. Coming from physics and engineering background I was fascinated by the richness and complexity of biological systems, posing great challenge to theoreticians. I previously worked on a number of theoretical problems in biology, including:

  1. The sources of protein abundance distributions in proliferating cell populations:

    • R. Arbel-Goren, A. Tal, T. Friedlander, S. Meshner, N. Costantino, D. L. Court and J. Stavans, "Effects of regulation by a small RNA on phenotypic variability in E. coli", Nucleic Acids Research, 1-10, March 2013; published online March 21, 2013 doi:10.1093/nar/gkt184.

  2. Signal processing in membrane proteins:

    • T. Friedlander and N. Brenner, "Adaptive response and enlargement of dynamic range", Mathematical Biosciences and Engineering8(2): 515-528, April 2011; (arXiv:1003.2791).
    • T. Friedlander and N. Brenner, "Adaptive Response by State-Dependent Inactivation", Proceedings of the National Academy of Sciences106(52):22558-22563, December 29, 2009; published online December 15, 2009, doi:10.1073/pnas.0902146106.

  3. The evolutionary origins of modularity in biological systems:

    • T. Friedlander, A. E. Mayo, T. Tlusty and U. Alon, "Mutation-rules and the evolution of sparseness and modularity in biological systems", PLoS One 8(8): e70444 (2013). doi:10.1371/journal.pone.0070444 (arXiv: 1302.4267).

 My current interest is in evolutionary biology. I recently joined IST as a post-doctoral fellow to broaden my knowledge in this field.