Dec 13, 2019
Making sense of signaling complexity
Date: December 13, 2019 |
3:00 pm –
4:00 pm
Speaker:
Michal Komorowski, IPPT PAN
Location: Mondi Seminar Room 3, Central Building
In the talk, I will present several findings inspired by mathematical information-theory that seem to contribute to reconciling the cross-wired architecture and cell-to-cell heterogeneity with the engineer’s expectations. Specifically, I will discuss
(i) possible evolutionary origins of cross-wired architecture,
(ii) sources of the cell-to-cell heterogeneity of signaling responses,
(iii) and implications of the above for the design of therapeutic interventions.