Selected Publications

Barton, N.H., Etheridge, and A.M., Veber, A. (2017). The infinitesimal model: definition, derivation and implications. Theoretical Population Biology, 118, 50-73.

Ringbauer, H., Coop, G., and Barton, N.H. (2017). Inferring recent demography from isolation by distance of long shared sequence blocks. Genetics, 205, 1335-1351.

Lohse, K., Chmelik, M., Martin, S.H., and Barton, N.H. (2016). Efficient strategies for calculating blockwise likelihoods under the coalescent. Genetics 202, 775-786.

Friedlander, T., Prizak, R., Guet, C., Barton, N.H., and Tkacik, G. (2016). Intrinsic limits to gene regulation by global crosstalk. Nature Communications, 7, 12307.

Barton, N.H., Briggs, D.E.G., Eisen, J.A., Goldstein, D.B., and Patel, N.H. (2007). Evolution. NY: Cold Spring Harbor Laboratory Press.

 

Publications (2013-2018)

 Barton, N.H. (2013). Differentiation. The Princeton Guide to Evolution. Ed. J. Losos, Princeton University Press.

Barton, N.H., Etheridge, A.M., and Véber, A. (2013). Modelling evolution in a spatial continuum. Journal of Statistical Physics.

Barton, N.H. (2013). Does hybridisation influence speciation? Journal of Evolutionary Biology, 26: 267-269.

Kelleher, J., Barton, N.H., and Etheridge A.M. (2013). Coalescent simulation in continuous space. Bioinformatics, 29: 955-956.

Barton N.H., Etheridge, A.M., Kelleher, J. and Véber A. (2013). Inference for the spatial lambda-Fleming-Viot process. Theoretical Population Biology, 87: 105-119.

Barton, N.H., Etheridge, A.M., Kelleher, J. and Véber, A. (2013). Genetic hitch-hiking in spatially extended populations. Theoretical Population Biology, 87: 75-89.

Paixão, T. and Barton, N.H. (2013). A variance decomposition approach to the analysis of genetic algorithms. GECCO'13 Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, 845-852.

Barton, N.H. and Paixão, T. (2013). Can quantitative and population genetics help us understand evolutionary computation? GECCO'13 Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, 1573-1580.

Hearn, J., Stone, G.N., Bunnefeld, L., Nicholls, J., Barton, N.H., Lohse, K. (2014). Likelihood-based inference of population history from low coverage de novo genome assemblies. Molecular Ecology, 23: 198-211.

Barton, N.H., Novak, S., and Paixão, T. (2014). Diverse forms of selection in evolution and computer science. (commentary)

Vladar, H.P., and Barton, N.H. (2014). Stability and response of polygenic traits to stabilizing selection and mutation. Genetics, 197:749-767.

Kelleher, J., Etheridge, A.M., and Barton, N.H. (2014). Coalescent simulation in continuous space: algorithms for large neighbourhood size. Theoretical Population Biology, 95: 13-23.

Barton, N.H. and Servedio, M.R. (2015). The interpretation of selection coefficients. Evolution, 69: 1101-1112.

Polechova, J., and Barton, N.H. (2015). Limits to adaptation along environmental gradients. PNAS (USA), 112: 6401-6406.

Paixão, T., Badkobehe, G., Barton, N.H., Dolgan, C., Dang, D.C., Friedrich, T., Lehre, P.K., Sudholt, D., and Trubenova, B. (2015). Towards a unifying framework for evolutionary processes. J. Theor. Biol., 383: 28-43.

Tugrul, M., Paixão, T., Barton, N.H., and Tkacik, G. (2015). Dynamics of transcription factor binding site evolution. PLoS Genetics, 11(11): e1005639.

Kelleher, J., Etheridge, A.M., Veber, A., and Barton, N.H. (2016). Spread of pedigree versus genetic ancestry in spatially distributed populations. Theoretical Population Biology, 108: 1-12.

Lohse, K., Chmelik, M., Martin, S.H., and Barton, N.H. (2016). Efficient strategies for calculating blockwise likelihoods under the coalescent. Genetics, 202: 775-786.

Paixao, T., and Barton, N.H. (2016). The effect of gene interactions on the long-term response to selection. PNAS, 113: 4422-4427.

Bod’ova, K., Tkacik, G., and Barton, N.H. (2016). A general approximation for the dynamics of quantitative traits. Genetics, 202: 1523-1548.

Friedlander, T., Prizak, R., Guet, C., Barton, and N.H., Tkacik, G. (2016). Intrinsic limits to gene regulation by global crosstalk. Nature Communications.

Abbott, R.J., Barton, N.H., and Good, J.M. (2016). Genomics of hybridization and its evolutionary consequences. Molecular Ecology, 25: 2325-2332.

Barton, N.H. (2016). Sewall Wright on evolution in Mendelian populations and the “shifting balance”. Genetics, 202: 3-4

Barton, N.H. (2016). Richard Hudson and Norman Kaplan on the coalescent process. Genetics, 202: 865-866

Franssen, S.U., Barton, N.H., and Schlötterer, C. (2017). Reconstruction of haplotype-blocks selected during experimental evolution. Mol. Biol. Evol., 34: 174-184.

Barton, N.H. (2017). How does epistasis influence the response to selection? Heredity, 118.1 (2017): 96-109.

Charlesworth, D., Barton, N.H., and Charlesworth, B. (2017). The sources of adaptive evolution. Proc. Roy. Soc. (Lond.) B, 284: 2016.2864

Ringbauer, H., Coop, G., and Barton, N.H. (2017). Inferring recent demography from isolation by distance of long shared sequence blocks. Genetics, 205: 1335-1351.

Turelli, M., and Barton, N.H. (2017). Deploying dengue-suppressing Wolbachia: robust models predict slow but effective spatial spread in Aedes aegypti. Theoretical Population Biology, 115: 45-60

Schmidt, T.L, Barton, N.H., Rasic, G., Turley, A.P., Montgomery, B.L., Iturbe-Ormaetxa, I., Cook, P.E., Ryan, P.A., Ritchie, S.A., Hoffmann, S.L., O’Neill, S.L., and Turelli, M. (2017). Successful local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti. PLoS Biology, DOI:10.1371/journal.pbio.2001894

Sachdeva, H., and Barton, N.H. (2017). Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow. Evolution.

Lagator, M., Paixao, T., Barton, N.H., and Guet, C. (2017). On the mechanistic nature of epistasis in a canonical cis-regulatory element. Elife, 6:e25192. DOI:10.7554/eLife.25192

Friedlander, T., Prizak, R., Barton, N.H., and Tkačik G. (2017). Evolution of new regulatory functions on biophysically realistic fitness landscapes. Nature Communications, 8: 216.

Novak, S., and Barton, N.H. (2017). When does frequency-independent selection maintain genetic variation? Genetics, 207: 653-668.

Barton, N.H., Etheridge, A.M., and Veber, A. (2017). The infinitesimal model: definition, derivation and implications. Theoretical Population Biology, 118: 50-73.

Charlesworth, B., and Barton. N.H. (2018). The spread of an inversion with migration and selection. Genetics, 208: 377-382.

Barton, N.H., and Etheridge, A.M. (2018). Establishment in a new habitat by polygenic adaptation. Theoretical Population Biology.

Ringbauer, H., Kolesnikov, A.S., Field, D.L., and Barton, N.H. (2018). Estimating barriers to gene flow from distorted isolation by distance patterns. Genetics.

Tavares, H., Whibley, A., Field, D.L., Bradley, D., Couchman, M., Copsey L.,, Burrus M, Andalo M, Li M, Li Q., Xue Y., Rebocho A.B., Barton N.H., and Coen E. (2018). Selection and gene flow shape genomic islands that control floral guides. (in review)

Payne, P., Geyrhofer, L., Barton, N.H., and Bollback, J.P. (2018). CRISPR-based herd immunity limits phage epidemics in bacterial populations. Elife.

Ellis, T., Field, D.L., and Barton N.H. (2018). Inference from paternity and sibships accounting for uncertainty in genealogy. (in review)

Sachdeva, H., and Barton, N.H. (2018). Introgression of a block of genome under infinitesimal selection. (in review)

Novembre, J., and Barton, N.H. (2018). Tread lightly interpreting polygenic tests of selection. (in review)

Bod’ova, K., Priklopil, T., Field, D.L., Barton, N.H., and Pickup, M. (2018). Evolutionary pathways for the generation of new self-incompatibility haplotypes in a non-self recognition system. (in review)