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Schur Group

Structural Biology of Cell Migration and Viral Infection

The Schur group aims to understand the structural and functional principles that control cell migration. In other projects the group tries to elucidate evolutionary conserved assembly and maturation mechanisms in retroviruses. To this end they use and develop advanced cryo-electron microscopy and image processing methods to study the structure and function of protein complexes in situ.

In the field of cell migration, the group focuses on the actin cytoskeleton, the key player allowing cells to move. Here they aim to obtain an understanding how cells dynamically and productively adapt the actin cytoskeleton to move in defined directions, by varying the activity of a large number of regulatory proteins.

In the field of virology, the group studies the structure of pleomorphic viruses by improving the versatility of cryo-EM data acquisition and the image processing methods. Specifically, the group is interested in the conservation and diversity of retroviral capsid assemblies, and why retroviruses developed a dependence on charge-compensatory molecules for assembly and maturation.

On this site:


Image of Lukas Bauer

Lukas Bauer

PhD Student

Image of Hanifatul Budiman

Hanifatul Budiman

PhD Student

Image of Darya Chernikova

Darya Chernikova

PhD Student

+43 2243 9000 0

Image of Julia Datler

Julia Datler

PhD Student

Image of Jesse Hansen

Jesse Hansen


Image of Manjunath Javoor

Manjunath Javoor

PhD Student

Image of Peter Kirchweger

Peter Kirchweger


Image of Mathias Percipalle

Mathias Percipalle

PhD Student

Image of Dario Porley

Dario Porley

PhD Student

Image of Francisco Rosario de Figueiredo

Francisco Rosario de Figueiredo


Image of Andreas Thader

Andreas Thader

Research Technician

Image of Bettina Zens

Bettina Zens


Current Projects

Cellular structural biology of the actin cytoskeleton and cell migration | Structural Conservation and Diversity of Retroviral Capsid | Cryo-electron tomography and image processing method development


Koch J, Xin Q, Obr M, Schäfer A, Rolfs N, Anagho HA, Kudulyte A, Woltereck L, Kummer S, Campos J, Uckeley ZM, Bell-Sakyi L, Kräusslich HG, Schur FK, Acuna C, Lozach PY. 2023. The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells. PLoS Pathogens. 19(8), e1011562. View

Fäßler F, Javoor M, Schur FK. 2023. Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM. Biochemical Society Transactions. 51(1), 87–99. View

Fäßler F, Javoor M, Datler J, Döring H, Hofer F, Dimchev GA, Hodirnau V-V, Faix J, Rottner K, Schur FK. 2023. ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. Science Advances. 9(3), add6495. View

Nicolas WJ, Fäßler F, Dutka P, Schur FK, Jensen G, Meyerowitz E. 2022. Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks. Current Biology. 32(11), P2375-2389. View

Obr M, Hagen WJH, Dick RA, Yu L, Kotecha A, Schur FK. 2022. Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs. Journal of Structural Biology. 214(2), 107852. View

View All Publications

ReX-Link: Florian Schur


since 2017 Assistant Professor, Institute of Science and Technology Austria (ISTA)
2016 – 2017 Postdoc, European Molecular Biology Laboratory, Heidelberg, Germany
2016 PhD, European Molecular Biology Laboratory, Heidelberg and University of Heidelberg, Germany

Selected Distinctions

2022    ERC Starting Grant
2021    FEBS Excellence Award
2021    EMBO Young Investigator
2021    ChanZuckerberg Initiative Visual proteomics grant
2020    FWF Standalone research grant
2018    FWF Standalone research grant
2016    Journal of Structural Biology, Paper of the Year Award

Additional Information

Download CV
View Schur group website

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