Skip to main content

Schur Group

Structural Biology of Cell Migration and Viral Infection

The Schur group aims to understand the structural and functional principles that control cell migration. In other projects, the group tries to elucidate assembly and maturation mechanisms in retroviruses and poxviruses. To this end, they use and develop advanced cryo-electron microscopy and image processing methods to study the structure and function of protein complexes in situ.
In the field of cell migration, the group focuses on the actin cytoskeleton, the key player allowing cells to move. Here they aim to obtain an understanding of how cells regulate directional cell movement by adapting the actin cytoskeleton via the intricate interplay of actin filament geometry and the activity of actin regulatory proteins.
In the field of virology, the group studies the structure of pleomorphic viruses by improving the versatility of cryo-EM data acquisition and image processing methods. Specifically, the group is interested in the conservation and diversity of retroviral capsid assemblies, and the assembly of poxviruses.


Image of Lukas Bauer

Lukas Bauer

PhD Student

Image of Hanifatul Budiman

Hanifatul Budiman

PhD Student

Image of Darya Chernikova

Darya Chernikova

PhD Student

+43 2243 9000 0

Image of Julia Datler

Julia Datler

PhD Student

Image of Jesse Hansen

Jesse Hansen


Image of Manjunath Javoor

Manjunath Javoor

PhD Student

Image of Peter Kirchweger

Peter Kirchweger


Image of Mathias Percipalle

Mathias Percipalle

PhD Student

Image of Dario Porley

Dario Porley

PhD Student

Image of Francisco Rosario de Figueiredo

Francisco Rosario de Figueiredo


Image of Andreas Thader

Andreas Thader

Research Technician

Image of Kain van den Elsen

Kain van den Elsen

Predoctoral Visiting Scientist

Image of Bettina Zens

Bettina Zens


Current Projects

Cellular structural biology of the actin cytoskeleton and cell migration | Structural assembly mechanisms of retroviral capsid proteins and poxvirus cores | Cryo-electron tomography and image processing method development


Zens B, Fäßler F, Hansen J, Hauschild R, Datler J, Hodirnau V-V, Zheden V, Alanko JH, Sixt MK, Schur FK. 2024. Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix. Journal of Cell Biology. 223(6), e202309125. View

Datler J, Hansen J, Thader A, Schlögl A, Bauer LW, Hodirnau V-V, Schur FK. 2024. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nature Structural & Molecular Biology. View

Dimchev GA, Amiri B, Fäßler F, Falcke M, Schur FK. 2023. Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data, Institute of Science and Technology Austria, 10.15479/AT:ISTA:14502. View

Koch J, Xin Q, Obr M, Schäfer A, Rolfs N, Anagho HA, Kudulyte A, Woltereck L, Kummer S, Campos J, Uckeley ZM, Bell-Sakyi L, Kräusslich HG, Schur FK, Acuna C, Lozach PY. 2023. The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells. PLoS Pathogens. 19(8), e1011562. View

Fäßler F, Javoor M, Schur FK. 2023. Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM. Biochemical Society Transactions. 51(1), 87–99. View

View All Publications

ReX-Link: Florian Schur


Since 2017 Assistant Professor, Institute of Science and Technology Austria (ISTA)
2016 – 2017 Postdoc, European Molecular Biology Laboratory, Heidelberg, Germany
2016 PhD, European Molecular Biology Laboratory, Heidelberg and University of Heidelberg, Germany

Selected Distinctions

2022    ERC Starting Grant
2021    FEBS Excellence Award
2021    EMBO Young Investigator
2021    ChanZuckerberg Initiative Visual proteomics grant
2020    FWF Standalone research grant
2018    FWF Standalone research grant
2016    Journal of Structural Biology, Paper of the Year Award

Additional Information

Download CV
View Schur group website

theme sidebar-arrow-up
Back to Top