Soft lithography is a technique used to imprint structures into mechanically soft materials from a master mould or stamp. This method of pattern transfer is used to make microfluidic devices for applications which require biocompatible materials such as Polydimethylsiloxane (PDMS). In the lab, a mixing machine is used to combine the two reagents bottles to form silicone without bubbles that cures in the oven. After mixing, the PDMS is poured on the micro fabricated channels, heated, and then peeled off the structures to make a device against a glass surface. A spin coater is also available to control the thickness of the membrane between layers forming the valves in multilayer soft lithography.
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